P37 CORTICOSTEROIDS THERAPY IN PATIENTS WITH RHEUMATOID ARTHRITIS
III Środkowo Europejski Kongres Osteoporozy i Osteoartrozy oraz XV Zjazd Polskiego Towarzystwa Osteoartrologii i Polskiej Fundacji Osteoporozy, Kraków 24-26.09.2009
Streszczenia:
Ortopedia Traumatologia Rehabilitacja 2009, vol 11 (Suppl. 2), s:153-154.
Ortopedia Traumatologia Rehabilitacja 2009, vol 11 (Suppl. 2), s:153-154.
P37
CORTICOSTEROIDS THERAPY IN PATIENTS WITH RHEUMATOID ARTHRITIS
Milenovic N.1, Popovic B.2, Vasic B.1
1 Special Hospital for Rheumatology Disease, Novi Sad, Serbia
2 Faculty of Medicine, University of Novi Sad, Serbia
Key words: Rheumatoid arthritis, glikocorticoides, therapy outcome
Introduction: Rheumatoid arthritis (RA) as autoimmune, inflammatory arthropathy required specific treatment which includes usage of glikocorticoides (GC).
Aim: The aim of study was to evaluate effect of GC therapy in patients with RA.
Material and methods: We examined 250 patients 57.26 years old (± 9.34 years), 77.67% was female patient, who suffered from RA 8.39 years (1-39 years), in 89.32% was RF positive RA.
Results: Patients used in 95.15% non-fluorides GC. Predominate form was oral application 57.29% (prednisone 41.75% and metilptrednisolon 15.54%), but in 33.98 was intramuscular application of metilprednisolon-acetat. Only 3.88% patients took combination. Stage or RA changes was classified with Stein-Brocker`s criteria and we found that 45.63% of our patients were in Grade 3 anatomical classification but 58.25% were in Grade 2 functional classification, but bettering functional capacity statistically significant correlated (r=0.2227, p=0.024) was GC application. Morning stiffness longer than 60 minutes had 54.37%. Serious adverse effect was not evidenced.
Conclusion: We can conclude that application of corticosteroids in treatment RA can be safe and beneficial for patient.